Compare between Enzyme and Coenzyme

Enzyme	Coenzyme
1.       Enzymes may protein catalysts that increase the rate of reactions.	1.        low molecular weight coenzymes are usually heat stable, dialyzable organic compounds.
2.       Enzyme does not undergo alteration during reaction.	2.        Coenzymes undergo alteration during the enzymatic reaction which is later, regenerated.
3.       rate of reaction increases through the activity of enzymes.	3.        Coenzymes function with the enzyme in the catalytic process.
4.       Do not perform as carrier of atom or functional group.	4.        Some coenzymes act as transient carrier of specific atom or functional group.
5.       Enzyme’s protein part is apoenzyme that is essential for enzymic activity.	5.        Coenzymes are covalently bound to the apoenzyme and function at or close the active site in catalysis.
6.       Enzymes are protein in nature with high molecular weight.	6.        Coenzymes are non-protein in nature and low molecular weight.
7.       Enzymes are also considered as apoenzyme which refers to the protein portion of the holoenxzyme (enzyme + cofactor)	7.        Coenzymes often regarded as the second substrates or co-substrate.
8.       They are heat and pH labile and non-dialyzable.	8.        They are heat and pH stable and dialyzable.
9.       Essentially all biochemical reactions are enzyme catalyzed.	9.        They play vital role in performing catalytic activity of enzyme.
10.    They are certainly produced by the body.	10.     These are vitamins derivatives.
11.    Enzymes can decrease the free energy of initiation of a reaction.	11.     They cannot do so without enzyme.
12.    Example: Transferases, Hydrolases	12.     Example: Thiamine pyrophosphate(TPP), Flavin adenine dinucleotide (FAD), Tetrahydrofolate (FH4) DETECTIONPROCESSES OF PATIENT NON-COMPLIANCE   Please click here you can know health information from my web site.